Review



p38 mapk inhibitor sb203580 sb  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 98
      Buy from Supplier

    Structured Review

    MedChemExpress p38 mapk inhibitor sb203580 sb
    P38 Mapk Inhibitor Sb203580 Sb, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 531 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/Adezmapimod/pm42153350-40-1-9
    Average 98 stars, based on 531 article reviews
    p38 mapk inhibitor sb203580 sb - by Bioz Stars, 2026-09
    98/100 stars

    Images

    Related Articles

    Infection:

    Article Title: Insufficient CXCL13 secretion in leprosy foamy macrophages attenuates lymphocyte recruitment and antimicrobial protein production.
    Article Snippet: THP-1 cells were differentiated into macrophages by PMA (200 ng/ml, Abcam). .. The cells were then pretreated with BAY 11-7085/ BAY 11-7083 (HY-10257, MCE), or p38 MAPK-IN-1 (HY-12839, MCE) for 0.5 hour before M. leprae infection. ..

    Article Title: Insufficient CXCL13 secretion in leprosy foamy macrophages attenuates lymphocyte recruitment and antimicrobial protein production
    Article Snippet: THP-1 cells were differentiated into macrophages by PMA (200 ng/ml, Abcam). .. The cells were then pretreated with BAY 11-7085/BAY 11-7083 (HY-10257, MCE), or p38 MAPK-IN-1 (HY-12839, MCE) for 0.5 hour before M. leprae infection. ..

    Injection:

    Article Title: Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps
    Article Snippet: .. 3 d after the injection of MC38 cells or patient organoids, Anti-CD3 Antibody (OKT-3) (3 mg/kg, HY-P990864, MedChemExpress, NJ, USA), Anumigilimab (2 mg/kg, HY-P99440, MedChemExpress), Ca 2+ channel agonist 1 (4 mg/kg, HY-41076, MedChemExpress), Clodronate Liposomes (40337ES08, Yeasen, China), DMSO (HY-Y0320C, MedChemExpress), DNase I (10 mg/kg, 10104159001, Merck), GSK484 hydrochloride (4 mg/kg, HY-100514, MedChemExpress), GSK583 (4 mg/kg, HY-100339, MedChemExpress), InVivoMAb anti-mouse CD3ε (5 mg/kg, catalog number: BE0001-1, clone name: 145-2C11, Bio X Cell, PA, USA), InVivoMAb anti-mouse Ly6G (5 mg/kg, catalog number: BE0075, clone name: RB6-8C5, Bio X Cell), InVivoMAb rat IgG2a isotype control (5 mg/kg, catalog number: BE0251, clone name: RG7/1.30, Bio X Cell), JNK-IN-8 (3 mg/kg, HY-13319, MedChemExpress), JSH-23 (5 mg/kg, HY-13982, MedChemExpress), MLKL-IN-1 (5 mg/kg, HY-139878, MedChemExpress), NOD1/2 antagonist-1 (5 mg/kg, HY-146034, MedChemExpress), Paquinimod (5 mg/kg, HY-100442, MedChemExpress), PMA (5 mg/kg, P8139, Merck), p38 MAPK-IN-1 (5 mg/kg, HY-12839, MedChemExpress), SCH772984 (3 mg/kg, HY-50846, MedChemExpress), Sparstolonin B (5 mg/kg, HY-116213, MedChemExpress), or Stattic (5 mg/kg, HY-13818, MedChemExpress) were injected into the tail vein of mice once every three days for a total of five times. .. Chemical induction of CRC model: Mice received an intraperitoneal injection of AOM (10 mg/kg, HY-111375, MedChemExpress) and were given regular water for 14 d, followed by 7 d of 2.5% DSS (HY-116282C, MedChemExpress) in place of regular water, then regular water again for 14 d, alternating between DSS and regular water.

    Article Title: Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps.
    Article Snippet: The specific details of this procedure were outlined as follows: After 3 d of the injection of MC38 cells or patient organoids, the bacteria (5 × 107 CFU/mouse in 100 μL DPBS) was injected into the posterior wall of the anus once every day for a total of ten times. (5) To eliminate the bacterial flora in mice, mice were orally fed with antibiotic premix (1 mL/kg/d, Metronidazole (1 mg/mL, M1547, Merck), Ampicillin (1 mg/mL, A5354, Merck), Neomycin (1 mg/mL, AR TI CL E IN P RE SS N1142, Merck), Gentamicin (1 mg/mL, G1914, Merck), and Vancomycin (0.5 mg/mL, V2002, Merck)) daily, and antibiotic premix (50 μL/mL) was added to the drinking water for 16 d. We used Normal Saline as the control. (6) Small molecule compound treatment: Before commencing the formal experiment, we gathered dosage data for the same drug or its structural analogues in mice of the same strain, emphasizing consistency in the administration route and experimental model. .. 3 d after the injection of MC38 cells or patient organoids, Anti-CD3 Antibody (OKT-3) (3 mg/kg, HY-P990864, MedChemExpress, NJ, USA), Anumigilimab (2 mg/kg, HY-P99440, MedChemExpress), Ca2+ channel agonist 1 (4 mg/kg, HY-41076, MedChemExpress), Clodronate Liposomes (40337ES08, Yeasen, China), DMSO (HY-Y0320C, MedChemExpress), DNase I (10 mg/kg, 10104159001, Merck), GSK484 hydrochloride (4 mg/kg, HY-100514, MedChemExpress), GSK583 (4 mg/kg, HY-100339, MedChemExpress), InVivoMAb anti-mouse CD3ε (5 mg/kg, catalog number: BE0001-1, clone name: 145-2C11, Bio X Cell, PA, USA), InVivoMAb anti-mouse Ly6G (5 mg/kg, catalog number: BE0075, clone name: RB6-8C5, Bio X Cell), InVivoMAb rat IgG2a isotype control (5 mg/kg, catalog number: BE0251, clone name: RG7/1.30, Bio X Cell), JNK-IN-8 (3 mg/kg, HY-13319, MedChemExpress), JSH23 (5 mg/kg, HY-13982, MedChemExpress), MLKL-IN-1 (5 mg/kg, HY-139878, MedChemExpress), NOD1/2 antagonist-1 (5 mg/kg, HY-146034, MedChemExpress), Paquinimod (5 mg/kg, HY-100442, MedChemExpress), PMA (5 mg/kg, P8139, Merck), p38 MAPK-IN-1 (5 mg/kg, HY-12839, MedChemExpress), SCH772984 (3 mg/kg, HY-50846, MedChemExpress), Sparstolonin B (5 mg/kg, HY-116213, MedChemExpress), or Stattic (5 mg/kg, HY-13818, MedChemExpress) were injected into the tail vein of mice once every three days for a total of five times. (7) Chemical induction of CRC model: Mice received an intraperitoneal injection of AOM (10 mg/kg, HY-111375, MedChemExpress) and were given regular water for 14 d, followed by 7 d of 2.5% DSS (HY-116282C, MedChemExpress) in place of regular water, then regular water again for 14 d, alternating between DSS and regular water. (8) Strategy for constructing Atf3, Hnrnpk, Ncf4, Relb, or Ripk2-cKO mouse model: We selected Exon2-Exon3 of Atf3 transcript-201 and Exon5-Exon8 of Hnrnpk-202 as the flox region, respectively. ..

    Liposomes:

    Article Title: Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps
    Article Snippet: .. 3 d after the injection of MC38 cells or patient organoids, Anti-CD3 Antibody (OKT-3) (3 mg/kg, HY-P990864, MedChemExpress, NJ, USA), Anumigilimab (2 mg/kg, HY-P99440, MedChemExpress), Ca 2+ channel agonist 1 (4 mg/kg, HY-41076, MedChemExpress), Clodronate Liposomes (40337ES08, Yeasen, China), DMSO (HY-Y0320C, MedChemExpress), DNase I (10 mg/kg, 10104159001, Merck), GSK484 hydrochloride (4 mg/kg, HY-100514, MedChemExpress), GSK583 (4 mg/kg, HY-100339, MedChemExpress), InVivoMAb anti-mouse CD3ε (5 mg/kg, catalog number: BE0001-1, clone name: 145-2C11, Bio X Cell, PA, USA), InVivoMAb anti-mouse Ly6G (5 mg/kg, catalog number: BE0075, clone name: RB6-8C5, Bio X Cell), InVivoMAb rat IgG2a isotype control (5 mg/kg, catalog number: BE0251, clone name: RG7/1.30, Bio X Cell), JNK-IN-8 (3 mg/kg, HY-13319, MedChemExpress), JSH-23 (5 mg/kg, HY-13982, MedChemExpress), MLKL-IN-1 (5 mg/kg, HY-139878, MedChemExpress), NOD1/2 antagonist-1 (5 mg/kg, HY-146034, MedChemExpress), Paquinimod (5 mg/kg, HY-100442, MedChemExpress), PMA (5 mg/kg, P8139, Merck), p38 MAPK-IN-1 (5 mg/kg, HY-12839, MedChemExpress), SCH772984 (3 mg/kg, HY-50846, MedChemExpress), Sparstolonin B (5 mg/kg, HY-116213, MedChemExpress), or Stattic (5 mg/kg, HY-13818, MedChemExpress) were injected into the tail vein of mice once every three days for a total of five times. .. Chemical induction of CRC model: Mice received an intraperitoneal injection of AOM (10 mg/kg, HY-111375, MedChemExpress) and were given regular water for 14 d, followed by 7 d of 2.5% DSS (HY-116282C, MedChemExpress) in place of regular water, then regular water again for 14 d, alternating between DSS and regular water.

    Article Title: Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps.
    Article Snippet: The specific details of this procedure were outlined as follows: After 3 d of the injection of MC38 cells or patient organoids, the bacteria (5 × 107 CFU/mouse in 100 μL DPBS) was injected into the posterior wall of the anus once every day for a total of ten times. (5) To eliminate the bacterial flora in mice, mice were orally fed with antibiotic premix (1 mL/kg/d, Metronidazole (1 mg/mL, M1547, Merck), Ampicillin (1 mg/mL, A5354, Merck), Neomycin (1 mg/mL, AR TI CL E IN P RE SS N1142, Merck), Gentamicin (1 mg/mL, G1914, Merck), and Vancomycin (0.5 mg/mL, V2002, Merck)) daily, and antibiotic premix (50 μL/mL) was added to the drinking water for 16 d. We used Normal Saline as the control. (6) Small molecule compound treatment: Before commencing the formal experiment, we gathered dosage data for the same drug or its structural analogues in mice of the same strain, emphasizing consistency in the administration route and experimental model. .. 3 d after the injection of MC38 cells or patient organoids, Anti-CD3 Antibody (OKT-3) (3 mg/kg, HY-P990864, MedChemExpress, NJ, USA), Anumigilimab (2 mg/kg, HY-P99440, MedChemExpress), Ca2+ channel agonist 1 (4 mg/kg, HY-41076, MedChemExpress), Clodronate Liposomes (40337ES08, Yeasen, China), DMSO (HY-Y0320C, MedChemExpress), DNase I (10 mg/kg, 10104159001, Merck), GSK484 hydrochloride (4 mg/kg, HY-100514, MedChemExpress), GSK583 (4 mg/kg, HY-100339, MedChemExpress), InVivoMAb anti-mouse CD3ε (5 mg/kg, catalog number: BE0001-1, clone name: 145-2C11, Bio X Cell, PA, USA), InVivoMAb anti-mouse Ly6G (5 mg/kg, catalog number: BE0075, clone name: RB6-8C5, Bio X Cell), InVivoMAb rat IgG2a isotype control (5 mg/kg, catalog number: BE0251, clone name: RG7/1.30, Bio X Cell), JNK-IN-8 (3 mg/kg, HY-13319, MedChemExpress), JSH23 (5 mg/kg, HY-13982, MedChemExpress), MLKL-IN-1 (5 mg/kg, HY-139878, MedChemExpress), NOD1/2 antagonist-1 (5 mg/kg, HY-146034, MedChemExpress), Paquinimod (5 mg/kg, HY-100442, MedChemExpress), PMA (5 mg/kg, P8139, Merck), p38 MAPK-IN-1 (5 mg/kg, HY-12839, MedChemExpress), SCH772984 (3 mg/kg, HY-50846, MedChemExpress), Sparstolonin B (5 mg/kg, HY-116213, MedChemExpress), or Stattic (5 mg/kg, HY-13818, MedChemExpress) were injected into the tail vein of mice once every three days for a total of five times. (7) Chemical induction of CRC model: Mice received an intraperitoneal injection of AOM (10 mg/kg, HY-111375, MedChemExpress) and were given regular water for 14 d, followed by 7 d of 2.5% DSS (HY-116282C, MedChemExpress) in place of regular water, then regular water again for 14 d, alternating between DSS and regular water. (8) Strategy for constructing Atf3, Hnrnpk, Ncf4, Relb, or Ripk2-cKO mouse model: We selected Exon2-Exon3 of Atf3 transcript-201 and Exon5-Exon8 of Hnrnpk-202 as the flox region, respectively. ..

    Control:

    Article Title: Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps
    Article Snippet: .. 3 d after the injection of MC38 cells or patient organoids, Anti-CD3 Antibody (OKT-3) (3 mg/kg, HY-P990864, MedChemExpress, NJ, USA), Anumigilimab (2 mg/kg, HY-P99440, MedChemExpress), Ca 2+ channel agonist 1 (4 mg/kg, HY-41076, MedChemExpress), Clodronate Liposomes (40337ES08, Yeasen, China), DMSO (HY-Y0320C, MedChemExpress), DNase I (10 mg/kg, 10104159001, Merck), GSK484 hydrochloride (4 mg/kg, HY-100514, MedChemExpress), GSK583 (4 mg/kg, HY-100339, MedChemExpress), InVivoMAb anti-mouse CD3ε (5 mg/kg, catalog number: BE0001-1, clone name: 145-2C11, Bio X Cell, PA, USA), InVivoMAb anti-mouse Ly6G (5 mg/kg, catalog number: BE0075, clone name: RB6-8C5, Bio X Cell), InVivoMAb rat IgG2a isotype control (5 mg/kg, catalog number: BE0251, clone name: RG7/1.30, Bio X Cell), JNK-IN-8 (3 mg/kg, HY-13319, MedChemExpress), JSH-23 (5 mg/kg, HY-13982, MedChemExpress), MLKL-IN-1 (5 mg/kg, HY-139878, MedChemExpress), NOD1/2 antagonist-1 (5 mg/kg, HY-146034, MedChemExpress), Paquinimod (5 mg/kg, HY-100442, MedChemExpress), PMA (5 mg/kg, P8139, Merck), p38 MAPK-IN-1 (5 mg/kg, HY-12839, MedChemExpress), SCH772984 (3 mg/kg, HY-50846, MedChemExpress), Sparstolonin B (5 mg/kg, HY-116213, MedChemExpress), or Stattic (5 mg/kg, HY-13818, MedChemExpress) were injected into the tail vein of mice once every three days for a total of five times. .. Chemical induction of CRC model: Mice received an intraperitoneal injection of AOM (10 mg/kg, HY-111375, MedChemExpress) and were given regular water for 14 d, followed by 7 d of 2.5% DSS (HY-116282C, MedChemExpress) in place of regular water, then regular water again for 14 d, alternating between DSS and regular water.

    Article Title: Effects of Mytilus edulis derived plasmalogens against atherosclerosis via lipid metabolism and MAPK signaling pathway
    Article Snippet: .. Subsequently, the membranes were washed with TBST three times, and incubated with the following primary antibodies: β-actin (HY- P80438 , MedChemExpress, Monmouth Junction, NJ, USA), p38 MAPK (HY- P80776 , MedChemExpress), Casp1 (ab138483, abcam, Cambridge, UK), Calm4 (ab2860, abcam), and Tnf (HY-P7090, MedChemExpress) at 4 °C overnight with agitation, followed by incubation with the second antibody for 4 h. The protein bands were visualized using electrochemiluminescence, and the intensity of bands was quantitatively analyzed using ImageJ software, with β-actin as the protein loading control. .. The experimental data were statistically analyzed using IBM SPSS Statistics 19.0 and GraphPad Prism 9.0 software.

    Article Title: Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps.
    Article Snippet: The specific details of this procedure were outlined as follows: After 3 d of the injection of MC38 cells or patient organoids, the bacteria (5 × 107 CFU/mouse in 100 μL DPBS) was injected into the posterior wall of the anus once every day for a total of ten times. (5) To eliminate the bacterial flora in mice, mice were orally fed with antibiotic premix (1 mL/kg/d, Metronidazole (1 mg/mL, M1547, Merck), Ampicillin (1 mg/mL, A5354, Merck), Neomycin (1 mg/mL, AR TI CL E IN P RE SS N1142, Merck), Gentamicin (1 mg/mL, G1914, Merck), and Vancomycin (0.5 mg/mL, V2002, Merck)) daily, and antibiotic premix (50 μL/mL) was added to the drinking water for 16 d. We used Normal Saline as the control. (6) Small molecule compound treatment: Before commencing the formal experiment, we gathered dosage data for the same drug or its structural analogues in mice of the same strain, emphasizing consistency in the administration route and experimental model. .. 3 d after the injection of MC38 cells or patient organoids, Anti-CD3 Antibody (OKT-3) (3 mg/kg, HY-P990864, MedChemExpress, NJ, USA), Anumigilimab (2 mg/kg, HY-P99440, MedChemExpress), Ca2+ channel agonist 1 (4 mg/kg, HY-41076, MedChemExpress), Clodronate Liposomes (40337ES08, Yeasen, China), DMSO (HY-Y0320C, MedChemExpress), DNase I (10 mg/kg, 10104159001, Merck), GSK484 hydrochloride (4 mg/kg, HY-100514, MedChemExpress), GSK583 (4 mg/kg, HY-100339, MedChemExpress), InVivoMAb anti-mouse CD3ε (5 mg/kg, catalog number: BE0001-1, clone name: 145-2C11, Bio X Cell, PA, USA), InVivoMAb anti-mouse Ly6G (5 mg/kg, catalog number: BE0075, clone name: RB6-8C5, Bio X Cell), InVivoMAb rat IgG2a isotype control (5 mg/kg, catalog number: BE0251, clone name: RG7/1.30, Bio X Cell), JNK-IN-8 (3 mg/kg, HY-13319, MedChemExpress), JSH23 (5 mg/kg, HY-13982, MedChemExpress), MLKL-IN-1 (5 mg/kg, HY-139878, MedChemExpress), NOD1/2 antagonist-1 (5 mg/kg, HY-146034, MedChemExpress), Paquinimod (5 mg/kg, HY-100442, MedChemExpress), PMA (5 mg/kg, P8139, Merck), p38 MAPK-IN-1 (5 mg/kg, HY-12839, MedChemExpress), SCH772984 (3 mg/kg, HY-50846, MedChemExpress), Sparstolonin B (5 mg/kg, HY-116213, MedChemExpress), or Stattic (5 mg/kg, HY-13818, MedChemExpress) were injected into the tail vein of mice once every three days for a total of five times. (7) Chemical induction of CRC model: Mice received an intraperitoneal injection of AOM (10 mg/kg, HY-111375, MedChemExpress) and were given regular water for 14 d, followed by 7 d of 2.5% DSS (HY-116282C, MedChemExpress) in place of regular water, then regular water again for 14 d, alternating between DSS and regular water. (8) Strategy for constructing Atf3, Hnrnpk, Ncf4, Relb, or Ripk2-cKO mouse model: We selected Exon2-Exon3 of Atf3 transcript-201 and Exon5-Exon8 of Hnrnpk-202 as the flox region, respectively. ..

    Incubation:

    Article Title: Effects of Mytilus edulis derived plasmalogens against atherosclerosis via lipid metabolism and MAPK signaling pathway
    Article Snippet: .. Subsequently, the membranes were washed with TBST three times, and incubated with the following primary antibodies: β-actin (HY- P80438 , MedChemExpress, Monmouth Junction, NJ, USA), p38 MAPK (HY- P80776 , MedChemExpress), Casp1 (ab138483, abcam, Cambridge, UK), Calm4 (ab2860, abcam), and Tnf (HY-P7090, MedChemExpress) at 4 °C overnight with agitation, followed by incubation with the second antibody for 4 h. The protein bands were visualized using electrochemiluminescence, and the intensity of bands was quantitatively analyzed using ImageJ software, with β-actin as the protein loading control. .. The experimental data were statistically analyzed using IBM SPSS Statistics 19.0 and GraphPad Prism 9.0 software.

    Electrochemiluminescence:

    Article Title: Effects of Mytilus edulis derived plasmalogens against atherosclerosis via lipid metabolism and MAPK signaling pathway
    Article Snippet: .. Subsequently, the membranes were washed with TBST three times, and incubated with the following primary antibodies: β-actin (HY- P80438 , MedChemExpress, Monmouth Junction, NJ, USA), p38 MAPK (HY- P80776 , MedChemExpress), Casp1 (ab138483, abcam, Cambridge, UK), Calm4 (ab2860, abcam), and Tnf (HY-P7090, MedChemExpress) at 4 °C overnight with agitation, followed by incubation with the second antibody for 4 h. The protein bands were visualized using electrochemiluminescence, and the intensity of bands was quantitatively analyzed using ImageJ software, with β-actin as the protein loading control. .. The experimental data were statistically analyzed using IBM SPSS Statistics 19.0 and GraphPad Prism 9.0 software.

    Mouse Assay:

    Article Title: Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps.
    Article Snippet: The specific details of this procedure were outlined as follows: After 3 d of the injection of MC38 cells or patient organoids, the bacteria (5 × 107 CFU/mouse in 100 μL DPBS) was injected into the posterior wall of the anus once every day for a total of ten times. (5) To eliminate the bacterial flora in mice, mice were orally fed with antibiotic premix (1 mL/kg/d, Metronidazole (1 mg/mL, M1547, Merck), Ampicillin (1 mg/mL, A5354, Merck), Neomycin (1 mg/mL, AR TI CL E IN P RE SS N1142, Merck), Gentamicin (1 mg/mL, G1914, Merck), and Vancomycin (0.5 mg/mL, V2002, Merck)) daily, and antibiotic premix (50 μL/mL) was added to the drinking water for 16 d. We used Normal Saline as the control. (6) Small molecule compound treatment: Before commencing the formal experiment, we gathered dosage data for the same drug or its structural analogues in mice of the same strain, emphasizing consistency in the administration route and experimental model. .. 3 d after the injection of MC38 cells or patient organoids, Anti-CD3 Antibody (OKT-3) (3 mg/kg, HY-P990864, MedChemExpress, NJ, USA), Anumigilimab (2 mg/kg, HY-P99440, MedChemExpress), Ca2+ channel agonist 1 (4 mg/kg, HY-41076, MedChemExpress), Clodronate Liposomes (40337ES08, Yeasen, China), DMSO (HY-Y0320C, MedChemExpress), DNase I (10 mg/kg, 10104159001, Merck), GSK484 hydrochloride (4 mg/kg, HY-100514, MedChemExpress), GSK583 (4 mg/kg, HY-100339, MedChemExpress), InVivoMAb anti-mouse CD3ε (5 mg/kg, catalog number: BE0001-1, clone name: 145-2C11, Bio X Cell, PA, USA), InVivoMAb anti-mouse Ly6G (5 mg/kg, catalog number: BE0075, clone name: RB6-8C5, Bio X Cell), InVivoMAb rat IgG2a isotype control (5 mg/kg, catalog number: BE0251, clone name: RG7/1.30, Bio X Cell), JNK-IN-8 (3 mg/kg, HY-13319, MedChemExpress), JSH23 (5 mg/kg, HY-13982, MedChemExpress), MLKL-IN-1 (5 mg/kg, HY-139878, MedChemExpress), NOD1/2 antagonist-1 (5 mg/kg, HY-146034, MedChemExpress), Paquinimod (5 mg/kg, HY-100442, MedChemExpress), PMA (5 mg/kg, P8139, Merck), p38 MAPK-IN-1 (5 mg/kg, HY-12839, MedChemExpress), SCH772984 (3 mg/kg, HY-50846, MedChemExpress), Sparstolonin B (5 mg/kg, HY-116213, MedChemExpress), or Stattic (5 mg/kg, HY-13818, MedChemExpress) were injected into the tail vein of mice once every three days for a total of five times. (7) Chemical induction of CRC model: Mice received an intraperitoneal injection of AOM (10 mg/kg, HY-111375, MedChemExpress) and were given regular water for 14 d, followed by 7 d of 2.5% DSS (HY-116282C, MedChemExpress) in place of regular water, then regular water again for 14 d, alternating between DSS and regular water. (8) Strategy for constructing Atf3, Hnrnpk, Ncf4, Relb, or Ripk2-cKO mouse model: We selected Exon2-Exon3 of Atf3 transcript-201 and Exon5-Exon8 of Hnrnpk-202 as the flox region, respectively. ..

    TUNEL Assay:

    Article Title: Ferulic Acid Combines with Ascorbic Acid to Target MMP9 to Attenuate Cisplatin-Induced Ototoxicity Through the p38MAPK Signaling Pathway
    Article Snippet: Paraformaldehyde (4%) and enhanced chemiluminescence detection (ECL) reagents were purchased from Biosharp (Hefei, China). .. A One-step TUNEL Apoptosis Detection Kit (C1088) was purchased from Biyuntian Biotechnology Co., Ltd. (Shanghai, China). p38 MAPK-IN-1 (HY-12839) was purchased from MedChemExpress (Monmouth Junction, NJ, USA). .. Anti-β-actin and Anti-GAPDH were purchased from Zhong Shan-Golden Bridge Biological Technology Co., Ltd. (Beijing, China).

    Article Title: Ferulic Acid Combines with Ascorbic Acid to Target MMP9 to Attenuate Cisplatin-Induced Ototoxicity Through the p38MAPK Signaling Pathway.
    Article Snippet: Paraformaldehyde (4%) and enhanced chemiluminescence detection (ECL) reagents were purchased from Biosharp (Hefei, China). .. A One-step TUNEL Apoptosis Detection Kit (C1088) was purchased from Biyuntian Biotechnology Co., Ltd. (Shanghai, China). p38 MAPK-IN-1 (HY-12839) was purchased from MedChemExpress (Monmouth Junction, NJ, USA). .. Anti-β-actin and Anti-GAPDH were purchased from Zhong Shan-Golden Bridge Biological Technology Co., Ltd. (Beijing, China).

    Blocking Assay:

    Article Title: TRIM38 Alleviates Ferroptosis in Heart Failure by Inactivating the TRAF6-p38 MAPK Pathway via Ubiquitinating Degradation of IRAK1.
    Article Snippet: This article explored the role of TRIM38 in ferroptosis in heart failure (HF) and its underlying mechanisms.. Methodologically, serum TRIM38, IRAK1 and TRAF6 proteins from HF patients were detected by Western blot.. In an in vitro study, an HF cell model was established by inducing H9c2 cells with doxorubicin.



    Similar Products

    p38 mapk inhibitor sb203580 sb  (MedChemExpress)
    98
    MedChemExpress p38 mapk inhibitor sb203580 sb
    P38 Mapk Inhibitor Sb203580 Sb, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/Adezmapimod/pm42153350-40-1-9
    Average 98 stars, based on 1 article reviews
    p38 mapk inhibitor sb203580 sb - by Bioz Stars, 2026-09
    98/100 stars
    		  Buy from Supplier
    p38  (Cell Signaling Technology Inc)
    99
    Cell Signaling Technology Inc p38
    P38, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/p38+MAPK+Antibody/pmc13019078-153-13-23
    Average 99 stars, based on 1 article reviews
    p38 - by Bioz Stars, 2026-09
    99/100 stars
    		  Buy from Supplier
    p p38  (Cell Signaling Technology Inc)
    99
    Cell Signaling Technology Inc p p38
    P P38, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/p38+MAPK+Antibody/pmc13019078-153-12-23
    Average 99 stars, based on 1 article reviews
    p p38 - by Bioz Stars, 2026-09
    99/100 stars
    		  Buy from Supplier
    p38 mapk  (MedChemExpress)
    97
    MedChemExpress p38 mapk
    P38 Mapk, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/Phospho-p38+alpha%2FMAPK14+(Thr180%2BTyr182)+Antibody/pm42418246-46-2-10
    Average 97 stars, based on 1 article reviews
    p38 mapk - by Bioz Stars, 2026-09
    97/100 stars
    		  Buy from Supplier
    p38 mapk rabbit ab  (Abmart Inc)
    86
    Abmart Inc p38 mapk rabbit ab
    The mRNA expression of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, <t>p38,</t> PI3K, Akt, Bax, Bcl2 , and Caspase 3 in E.tenella host cells.
    P38 Mapk Rabbit Ab, supplied by Abmart Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/anti+p38/pmc13125192-264-62-99
    Average 86 stars, based on 1 article reviews
    p38 mapk rabbit ab - by Bioz Stars, 2026-09
    86/100 stars
    		  Buy from Supplier
    p p38 mapk rabbit ab  (Abmart Inc)
    86
    Abmart Inc p p38 mapk rabbit ab
    The mRNA expression of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, <t>p38,</t> PI3K, Akt, Bax, Bcl2 , and Caspase 3 in E.tenella host cells.
    P P38 Mapk Rabbit Ab, supplied by Abmart Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/anti+p38/pmc13125192-124-0-5
    Average 86 stars, based on 1 article reviews
    p p38 mapk rabbit ab - by Bioz Stars, 2026-09
    86/100 stars
    		  Buy from Supplier
    p38 mapk inhibitor sb203580  (MedChemExpress)
    98
    MedChemExpress p38 mapk inhibitor sb203580
    TLCA regulates mitochondrial biogenesis and altered myofiber type composition through the <t>p38</t> MAPK/PGC-1α signaling pathway. A Cell viability of cells treated with different concentrations of TLCA for 24 h (n = 10). B & F The mRNA expression of MYH1A and MYH7B (n = 6). C & G Intracellular enzymatic activities of succinate dehydrogenase (SDH) and lactate dehydrogenase (LDH), ATP content and mitochondrial DNA (mtDNA) content (n = 6). D & H The mRNA expression of HK1, GPI, PGAM1, PGK1, PYGL, PGC-1α, NRF1 and TFAM (n = 6). E The protein expression of PGC-1α, <t>p38</t> <t>MAPK</t> and phosphorylation p38 MAPK (n = 3). I The protein expression of PGC-1α (n = 3). Data were shown as mean ± SD; *Represents significant difference when compared with 0 μM TLCA or CON group, and # represents significant difference when compared with TLCA group. *& # P < 0.05, ⁎⁎ & ## P < 0.01, ⁎⁎⁎ & ### P < 0.001.
    P38 Mapk Inhibitor Sb203580, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/Adezmapimod/pmc13122816-73-6-11
    Average 98 stars, based on 1 article reviews
    p38 mapk inhibitor sb203580 - by Bioz Stars, 2026-09
    98/100 stars
    		  Buy from Supplier
    phospho p38 mapk  (Cell Signaling Technology Inc)
    98
    Cell Signaling Technology Inc phospho p38 mapk
    TLCA regulates mitochondrial biogenesis and altered myofiber type composition through the <t>p38</t> MAPK/PGC-1α signaling pathway. A Cell viability of cells treated with different concentrations of TLCA for 24 h (n = 10). B & F The mRNA expression of MYH1A and MYH7B (n = 6). C & G Intracellular enzymatic activities of succinate dehydrogenase (SDH) and lactate dehydrogenase (LDH), ATP content and mitochondrial DNA (mtDNA) content (n = 6). D & H The mRNA expression of HK1, GPI, PGAM1, PGK1, PYGL, PGC-1α, NRF1 and TFAM (n = 6). E The protein expression of PGC-1α, <t>p38</t> <t>MAPK</t> and phosphorylation p38 MAPK (n = 3). I The protein expression of PGC-1α (n = 3). Data were shown as mean ± SD; *Represents significant difference when compared with 0 μM TLCA or CON group, and # represents significant difference when compared with TLCA group. *& # P < 0.05, ⁎⁎ & ## P < 0.01, ⁎⁎⁎ & ### P < 0.001.
    Phospho P38 Mapk, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/p38+mapk/Phospho-p38+MAPK+(Thr180%2FTyr182)+XP+Rabbit+mAb/pmc13049640-314-23-25
    Average 98 stars, based on 1 article reviews
    phospho p38 mapk - by Bioz Stars, 2026-09
    98/100 stars
    		  Buy from Supplier

    Image Search Results


    The mRNA expression of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, p38, PI3K, Akt, Bax, Bcl2 , and Caspase 3 in E.tenella host cells.

    Journal: Poultry Science

    Article Title: Pathogenic mechanism of Eimeria tenella Et MIC2 promotes Eimeria tenella invasion and inhibits host cell apoptosis through binding to the ITGAV receptor

    doi: 10.1016/j.psj.2026.106922

    Figure Lengend Snippet: The mRNA expression of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, p38, PI3K, Akt, Bax, Bcl2 , and Caspase 3 in E.tenella host cells.

    Article Snippet: Membranes were blocked with 5 % BSA at 37°C for 2 h and incubated overnight at 4°C with the following primary antibodies: ITGAV Rabbit Ab, PLC Rabbit Ab, p-PLC Rabbit Ab, p-p65 Rabbit Ab, and Bcl2 Rabbit Ab were purchased from Bioss (Beijing, China); FAK Rabbit Ab, p-FAK Rabbit Ab, ERK Rabbit Ab, p-ERK Rabbit Ab, JNK Rabbit Ab, p-JNK Rabbit Ab, p38 MAPK Rabbit Ab, p-p38 MAPK Rabbit Ab, PI3K Rabbit Ab, p-PI3K Rabbit Ab, AKT Rabbit Ab, p-AKT Rabbit Ab, PKC Rabbit Ab, p-PKC Rabbit Ab, Bax Rabbit Ab, and Caspase 3 Rabbit Ab were purchased from Abmart (Shanghai, China); p65 Rabbit Ab (Proteintech, Wuhan, China).

    Techniques: Expressing

    The protein activity changes of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, p38, PI3K, Akt, Bax, Bcl2, and Caspase 3 in E.tenella host cells.

    Journal: Poultry Science

    Article Title: Pathogenic mechanism of Eimeria tenella Et MIC2 promotes Eimeria tenella invasion and inhibits host cell apoptosis through binding to the ITGAV receptor

    doi: 10.1016/j.psj.2026.106922

    Figure Lengend Snippet: The protein activity changes of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, p38, PI3K, Akt, Bax, Bcl2, and Caspase 3 in E.tenella host cells.

    Article Snippet: Membranes were blocked with 5 % BSA at 37°C for 2 h and incubated overnight at 4°C with the following primary antibodies: ITGAV Rabbit Ab, PLC Rabbit Ab, p-PLC Rabbit Ab, p-p65 Rabbit Ab, and Bcl2 Rabbit Ab were purchased from Bioss (Beijing, China); FAK Rabbit Ab, p-FAK Rabbit Ab, ERK Rabbit Ab, p-ERK Rabbit Ab, JNK Rabbit Ab, p-JNK Rabbit Ab, p38 MAPK Rabbit Ab, p-p38 MAPK Rabbit Ab, PI3K Rabbit Ab, p-PI3K Rabbit Ab, AKT Rabbit Ab, p-AKT Rabbit Ab, PKC Rabbit Ab, p-PKC Rabbit Ab, Bax Rabbit Ab, and Caspase 3 Rabbit Ab were purchased from Abmart (Shanghai, China); p65 Rabbit Ab (Proteintech, Wuhan, China).

    Techniques: Activity Assay

    The mRNA expression of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, p38, PI3K, Akt, Bax, Bcl2 , and Caspase 3 in E.tenella host cells.

    Journal: Poultry Science

    Article Title: Pathogenic mechanism of Eimeria tenella Et MIC2 promotes Eimeria tenella invasion and inhibits host cell apoptosis through binding to the ITGAV receptor

    doi: 10.1016/j.psj.2026.106922

    Figure Lengend Snippet: The mRNA expression of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, p38, PI3K, Akt, Bax, Bcl2 , and Caspase 3 in E.tenella host cells.

    Article Snippet: p-p38 MAPK Rabbit Ab , Abmart , TA4001 , 1: 1500.

    Techniques: Expressing

    The protein activity changes of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, p38, PI3K, Akt, Bax, Bcl2, and Caspase 3 in E.tenella host cells.

    Journal: Poultry Science

    Article Title: Pathogenic mechanism of Eimeria tenella Et MIC2 promotes Eimeria tenella invasion and inhibits host cell apoptosis through binding to the ITGAV receptor

    doi: 10.1016/j.psj.2026.106922

    Figure Lengend Snippet: The protein activity changes of ITGAV, FAK, PLC, PKC, p65, ERK, JNK, p38, PI3K, Akt, Bax, Bcl2, and Caspase 3 in E.tenella host cells.

    Article Snippet: p-p38 MAPK Rabbit Ab , Abmart , TA4001 , 1: 1500.

    Techniques: Activity Assay

    TLCA regulates mitochondrial biogenesis and altered myofiber type composition through the p38 MAPK/PGC-1α signaling pathway. A Cell viability of cells treated with different concentrations of TLCA for 24 h (n = 10). B & F The mRNA expression of MYH1A and MYH7B (n = 6). C & G Intracellular enzymatic activities of succinate dehydrogenase (SDH) and lactate dehydrogenase (LDH), ATP content and mitochondrial DNA (mtDNA) content (n = 6). D & H The mRNA expression of HK1, GPI, PGAM1, PGK1, PYGL, PGC-1α, NRF1 and TFAM (n = 6). E The protein expression of PGC-1α, p38 MAPK and phosphorylation p38 MAPK (n = 3). I The protein expression of PGC-1α (n = 3). Data were shown as mean ± SD; *Represents significant difference when compared with 0 μM TLCA or CON group, and # represents significant difference when compared with TLCA group. *& # P < 0.05, ⁎⁎ & ## P < 0.01, ⁎⁎⁎ & ### P < 0.001.

    Journal: Poultry Science

    Article Title: Gut microbiota-derived taurolithocholic acid modulates myofiber-type switching via p38 MAPK/PGC-1α signaling underlying breed differences between Arbor Acres and Taoyuan chickens

    doi: 10.1016/j.psj.2026.106914

    Figure Lengend Snippet: TLCA regulates mitochondrial biogenesis and altered myofiber type composition through the p38 MAPK/PGC-1α signaling pathway. A Cell viability of cells treated with different concentrations of TLCA for 24 h (n = 10). B & F The mRNA expression of MYH1A and MYH7B (n = 6). C & G Intracellular enzymatic activities of succinate dehydrogenase (SDH) and lactate dehydrogenase (LDH), ATP content and mitochondrial DNA (mtDNA) content (n = 6). D & H The mRNA expression of HK1, GPI, PGAM1, PGK1, PYGL, PGC-1α, NRF1 and TFAM (n = 6). E The protein expression of PGC-1α, p38 MAPK and phosphorylation p38 MAPK (n = 3). I The protein expression of PGC-1α (n = 3). Data were shown as mean ± SD; *Represents significant difference when compared with 0 μM TLCA or CON group, and # represents significant difference when compared with TLCA group. *& # P < 0.05, ⁎⁎ & ## P < 0.01, ⁎⁎⁎ & ### P < 0.001.

    Article Snippet: The differentiation medium containing TLCA and p38 MAPK inhibitor SB203580 (152121-47-6, MedChemExpress, Shanghai, China) was added to CPMs after 4 days of differentiation, and the cells were collected after 24 h.

    Techniques: Expressing, Phospho-proteomics